A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop
Structural snapshots of protein/ligand complexes are a prerequisite for gaining atomic level insight into enzymatic reaction mechanisms. An important group of enzymes has been deprived of this analytical privilege: members of the protein tyrosine phosphatase (PTP) superfamily with catalytic WPD-loop...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Nature Research
2022
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