A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop

Structural snapshots of protein/ligand complexes are a prerequisite for gaining atomic level insight into enzymatic reaction mechanisms. An important group of enzymes has been deprived of this analytical privilege: members of the protein tyrosine phosphatase (PTP) superfamily with catalytic WPD-loop...

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Bibliographic Details
Main Authors: Wang, H, Perera, L, Jork, N, Riley, AM, Potter, BVL, Et al.
Format: Journal article
Language:English
Published: Nature Research 2022