Pseudotyped influenza A virus as a vaccine for the induction of heterotypic immunity.

There is a need for vaccines that can protect broadly across all influenza A strains. We have produced a pseudotyped influenza virus based on suppression of the A/PR/8/34 hemagglutinin signal sequence (S-FLU) that can infect cells and express the viral core proteins and neuraminidase but cannot repl...

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Bibliographic Details
Main Authors: Powell, T, Silk, J, Sharps, J, Fodor, E, Townsend, A
Format: Journal article
Language:English
Published: 2012