Pseudotyped influenza A virus as a vaccine for the induction of heterotypic immunity.
There is a need for vaccines that can protect broadly across all influenza A strains. We have produced a pseudotyped influenza virus based on suppression of the A/PR/8/34 hemagglutinin signal sequence (S-FLU) that can infect cells and express the viral core proteins and neuraminidase but cannot repl...
Main Authors: | Powell, T, Silk, J, Sharps, J, Fodor, E, Townsend, A |
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Format: | Journal article |
Language: | English |
Published: |
2012
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