Delta-like ligand 4-notch blockade and tumor radiation response.

BACKGROUND: The microenvironment plays an important role in regulating tumor response to radiotherapy. Ionizing radiation can disrupt tumor vasculature, and Notch pathway inhibition can interfere with functional angiogenesis. We explored the potential cooperativity between Notch inhibition and ioni...

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Bibliographic Details
Main Authors: Liu, S, Bham, SA, Fokas, E, Beech, J, Im, J, Cho, S, Harris, A, Muschel, R
Format: Journal article
Language:English
Published: 2011