An OMV vaccine derived from a capsular group B meningococcus with constitutive FetA expression: preclinical evaluation of immunogenicity and toxicity

Following the introduction of effective protein-polysaccharide conjugate vaccines against capsular group C meningococcal disease in Europe, meningococci of capsular group B remain a major cause of death and can result in debilitating sequelae. The outer membrane proteins PorA and FetA have previousl...

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Bibliographic Details
Main Authors: Norheim, G, Sanders, H, Mellesdal, J, Sundfør, I, Chan, H, Brehony, C, Vipond, C, Dold, C, Care, R, Saleem, M, Maiden, M, Derrick, J, Feavers, I, Pollard, A
Format: Journal article
Language:English
Published: Public Library of Science 2015