Oxygenase catalyzed 5-methylcytosine hydroxylation.

Recent reports identify the oxygenase catalyzed production of 5-hydroxymethylcytosine as a modification to mammalian DNA (Kriaucionis and Heintz, 2009; Tahiliani et al., 2009). This discovery has potential far-reaching implications for epigenetic regulation and will stimulate efforts to identify new...

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Bibliographic Details
Main Authors: Loenarz, C, Schofield, C
Format: Journal article
Language:English
Published: 2009