Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1.

E-selectin is an endothelial adhesion molecule, which mediates the tethering and rolling of leukocytes on vascular endothelium. It recognizes the glycoprotein E-selectin ligand-1 (ESL-1) as a major binding partner on mouse myeloid cells. Using surface plasmon resonance, we measured the kinetics and...

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Hlavní autoři: Wild, M, Huang, M, Schulze-Horsel, U, Van Der Merwe, P, Vestweber, D
Médium: Journal article
Jazyk:English
Vydáno: 2001