The stereoselective birch reduction of pyrroles

The Birch reduction has been applied to electron-deficient pyrroles substituted with a chiral auxiliary at the C-2 position. Using either 8- phenylmenthol or trans-2-(α-cumyl)cyclohexanol (TCC) as auxiliaries, high levels of stereoselectivity were obtained. Moreover, the auxiliary could be removed u...

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Bibliographic Details
Main Authors: Donohoe, T, Guyo, P, Helliwell, M
Format: Journal article
Language:English
Published: 1999