A novel domain cassette identifies Plasmodium falciparum PfEMP1 proteins binding ICAM-1 and is a target of cross-reactive, adhesion-inhibitory antibodies.

Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites expressing the structurally related group A subset of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family of IE adhesion...

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Príomhchruthaitheoirí: Bengtsson, A, Joergensen, L, Rask, T, Olsen, R, Andersen, M, Turner, L, Theander, T, Hviid, L, Higgins, M, Craig, A, Brown, A, Jensen, A
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2013