Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue.

Limitations on the number of unique protein and DNA molecules that can be characterized microscopically in a single tissue specimen impede advances in understanding the biological basis of health and disease. Here we present a multiplexed fluorescence microscopy method (MxIF) for quantitative, singl...

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Bibliographic Details
Main Authors: Gerdes, M, Sevinsky, C, Sood, A, Adak, S, Bello, M, Bordwell, A, Can, A, Corwin, A, Dinn, S, Filkins, R, Hollman, D, Kamath, V, Kaanumalle, S, Kenny, K, Larsen, M, Lazare, M, Li, Q, Lowes, C, McCulloch, C, McDonough, E, Montalto, M, Pang, Z, Rittscher, J, Santamaria-Pang, A, Sarachan, B
Format: Journal article
Language:English
Published: 2013