Control of NFAT isoform activation and NFAT-dependent gene expression through two coincident and spatially segregated intracellular Ca(2+) signals

Excitation-transcription coupling, linking stimulation at the cell surface to changes in nuclear gene expression, is conserved throughout eukaryotes. How closely related coexpressed transcription factors are differentially activated remains unclear. Here, we show that two Ca(2+)-dependent transcript...

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Bibliographic Details
Main Authors: Kar, P, Mirams, G, Christian, H, Parekh, A
Format: Journal article
Language:English
Published: Cell Press 2016