Cholesterol depletion of hepatoma cells impairs hepatitis B virus envelopment by altering the topology of the large envelope protein
Previous reports have shown that cholesterol depletion of the membrane envelope of the hepatitis B virus (HBV) impairs viral infection of target cells. A potential function of this lipid in later steps of the viral life cycle remained controversial, with secretion of virions and subviral particles (...
Main Authors: | Dorobantu, C, Macovei, A, Lazar, C, Dwek, R, Zitzmann, N, Branza-Nichita, N |
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格式: | Journal article |
语言: | English |
出版: |
American Society for Microbiology
2011
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