Selectivity in the cycloadditions of carbonyl ylides with glyoxylates: an approach to the zaragozic acids-squalestatins

Reaction of diazodiketoester 8 with glyoxylates in the presence of catalytic rhodium(n) acetate generates 6,8-dioxabicyclo[3.2.1]octanes 9 and 11 in good yield. Elaboration of 9 provides a suitable alcohol 25 for acid-catalysed rearrangement to give the 2,8-dioxabicyclo[3.2.1]octane skeleton 26 of t...

詳細記述

書誌詳細
主要な著者: Hodgson, D, Bailey, J, Villalonga-Barber, C, Drew, M, Harrison, T
フォーマット: Journal article
言語:English
出版事項: 2000