IFN-gamma exposes a cryptic cytotoxic T lymphocyte epitope in HIV-1 reverse transcriptase.

IFN-gamma exposes a cryptic cytotoxic T lymphocyte epitope in HIV-1 reverse transcriptase.

The proteasome, an essential component of the ATP-dependent proteolytic pathway in eukaryotic cells, is responsible for the degradation of most cellular proteins and is believed to be the main source of MHC class I-restricted antigenic peptides for presentation to CTL. Inhibition of the proteasome b...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Sewell, A, Price, D, Teisserenc, H, Booth, B, Gileadi, U, Flavin, F, Trowsdale, J, Phillips, R, Cerundolo, V
Format:	Journal article
Sprache:	English
Veröffentlicht:	1999

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