IFN-gamma exposes a cryptic cytotoxic T lymphocyte epitope in HIV-1 reverse transcriptase.
The proteasome, an essential component of the ATP-dependent proteolytic pathway in eukaryotic cells, is responsible for the degradation of most cellular proteins and is believed to be the main source of MHC class I-restricted antigenic peptides for presentation to CTL. Inhibition of the proteasome b...
主要な著者: | Sewell, A, Price, D, Teisserenc, H, Booth, B, Gileadi, U, Flavin, F, Trowsdale, J, Phillips, R, Cerundolo, V |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1999
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