The D2 antagonist sulpiride modulates the neural processing of both rewarding and aversive stimuli in healthy volunteers

Rationale Animal studies indicate that dopamine pathways in the ventral striatum code for the motivational salience of both rewarding and aversive stimuli, but evidence for this mechanism in humans is less established. We have developed a functional magnetic resonance imaging (fMRI) model which perm...

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Bibliographic Details
Main Authors: McCabe, C, Huber, A, Harmer, C, Cowen, P
Format: Journal article
Language:English
Published: 2011