Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system

The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has recently emerged as a leading candidate antigen against the blood-stage human malaria parasite. However it has proved challenging to identify a heterologous expression platform that can produce a soluble protein-based vacci...

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Bibliographic Details
Main Authors: Hjerrild, K, Jin, J, Wright, K, Brown, R, Marshall, J, Labbe, G, Silk, S, Cherry, C, Clemmensen, S, Jørgensen, T, Illingworth, J, Alanine, D, Milne, K, Ashfield, R, de Jongh, W, Douglas, A, Higgins, M, Draper, S
Format: Journal article
Published: Nature Publishing Group 2016