The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.

The ASPP1 (Apoptosis Stimulating Protein of p53) protein is an important tumour-suppressor. We have detected a novel protein interaction between the human ASPP1 (hASPP1) protein and the predominantly nuclear adaptor protein SAM68. In the human testis, full-length endogenous hASPP1 protein is located...

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Bibliographic Details
Main Authors: Thornton, J, Dalgleish, C, Venables, J, Sergeant, K, Ehrmann, I, Lu, X, Saunders, P, Elliott, D
Format: Journal article
Language:English
Published: 2006