Site-selective chemical protein glycosylation protects from autolysis and proteolytic degradation.

Glycosylation is often cited as having a stabilizing effect upon proteins with respect to proteolysis, thermolysis and other forms of degradation. We present here a model study on an autolytic protease that has been chemically glycosylated to produce single glycoforms. The resulting glycosylated enz...

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Bibliographic Details
Main Authors: Russell, D, Oldham, N, Davis, B
Format: Journal article
Language:English
Published: 2009