An investigation of enzyme mechanisms using substrate analogues
<p>The synthesis of several fluorinated analogues of thiamine and precursors has been undertaken, all of which exhibit weak activity against <em>E.Coli</em>. A route to 3-fluoro-(<em>R</em>)-alanine has been explored.</p> <p>The first synthesis of the enant...
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Format: | Thesis |
Language: | English |
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1980
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