Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993.

Outcome of acute lymphoblastic leukemia (ALL) in adults with central nervous system (CNS) disease at diagnosis is unclear. We treated 1508 de novo ALL patients with 2-phase induction and then high-dose methotrexate with l-asparaginase. Patients up to 50 years old in first remission (CR1) with a matc...

Полное описание

Библиографические подробности
Главные авторы: Lazarus, H, Richards, S, Chopra, R, Litzow, MR, Burnett, A, Wiernik, P, Franklin, I, Tallman, MS, Cook, L, Buck, G, Durrant, I, Rowe, J, Goldstone, A
Формат: Journal article
Язык:English
Опубликовано: 2006