Asymmetric alkylations using SuperQuat auxiliaries - an investigation into the synthesis and stability of enolates derived from 5,5-disubstituted oxazolidin-2-ones
Studies on the alkylation of enolates derived from a range of W-acyl-5,5-dimethyloxazolidin-2-ones and N-acyl-5,5diphenyloxazolidin-2-ones reveal that high yields and high diastereoselectivities are best obtained when homochiral 4-isopropyl-5,5-dimethyIoxazolidin-2-one is employed as a chiral auxili...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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