TGFβ counteracts LYVE-1-mediated induction of lymphangiogenesis by small hyaluronan oligosaccharides

During tissue injury, inflammation, and tumor growth, enhanced production and degradation of the extracellular matrix glycosaminoglycan hyaluronan (HA) can lead to the accumulation of small HA (sHA) oligosaccharides. We have previously reported that accumulation of sHA in colorectal tumors correlate...

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Bibliographic Details
Main Authors: Bauer, J, Rothley, M, Schmaus, A, Quagliata, L, Ehret, M, Biskup, M, Orian-Rousseau, V, Jackson, D, Pettis, R, Harvey, A, Bräse, S, Thiele, W, Sleeman, J
Format: Journal article
Language:English
Published: Springer Verlag 2017