Placental syncytiotrophoblast-derived extracellular vesicles carry active NEP (neprilysin) and are increased in preeclampsia
NEP (neprilysin) is a widely expressed membrane-bound metalloprotease, which binds and cleaves a variety of peptides including vasodilators, natriuretics, and diuretics. Higher levels of NEP result in hypertension—a cardinal feature of the placental disease preeclampsia. Syncytiotrophoblast-derived...
Váldodahkkit: | Gill, M, Motta-Mejia, C, Kandzija, N, Cooke, W, Zhang, W, Cerdeira, S, Bastie, C, Redman, C, Vatish, M |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
American Heart Association
2019
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Geahča maid
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