Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma

Decysin-1 (ADAMDEC1) is an orphan ADAM-like metalloprotease with unknown biological function and a short domain structure. ADAMDEC1 mRNA has previously been demonstrated primarily in macrophages and mature dendritic cells. Here, we generated monoclonal antibodies (mAbs) against the mature ADAMDEC1 p...

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Hlavní autoři: Lund, J, Elimar Bitsch, A, Grønbech Rasch, M, Enoksson, M, Troeberg, L, Nagase, H, Loftager, M, Overgaard, M, Petersen, H
Médium: Journal article
Jazyk:English
Vydáno: Taylor and Francis 2017

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