Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia

Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia

BACKGROUND: Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whether cell-free Hb a...

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Dades bibliogràfiques
Autors principals:	Cronqvist, T, Saljé, K, Familari, M, Guller, S, Schneider, H, Gardiner, C, Sargent, I, Redman, C, Mörgelin, M, Åkerström, B, Gram, M, Hansson, SR
Format:	Journal article
Idioma:	English
Publicat:	Public Library of Science 2014

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