Syncytiotrophoblast vesicles show altered micro-RNA and haemoglobin content after ex-vivo perfusion of placentas with haemoglobin to mimic preeclampsia
BACKGROUND: Cell-free foetal haemoglobin (HbF) has been shown to play a role in the pathology of preeclampsia (PE). In the present study, we aimed to further characterize the harmful effects of extracellular free haemoglobin (Hb) on the placenta. In particular, we investigated whether cell-free Hb a...
Main Authors: | Cronqvist, T, Saljé, K, Familari, M, Guller, S, Schneider, H, Gardiner, C, Sargent, I, Redman, C, Mörgelin, M, Åkerström, B, Gram, M, Hansson, SR |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
Public Library of Science
2014
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