Exploiting rhodium-catalysed ynamide hydroacylation as a platform for divergent heterocycle synthesis

The first examples of ynamide hydroacylation are described. Using rhodium catalysis, linear β-enaminone products are generated in high yield and excellent regioselectivity from the combination of aldehydes and ynamides. The enaminone products are subsequently used as a platform to construct a divers...

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Bibliographic Details
Main Authors: Straker, R, Majhail, M, Willis, M
Format: Journal article
Published: Royal Society of Chemistry 2017