RASSF1A regulation of transcription factors in tumourigenesis and stem cell fate determination
RASSF1A silencing is the most widely reported epigenetic event in sporadic human malignancies and is increasingly observed to be associated with poorer prognosis and outcome in lung, breast and bladder cancers amongst others. By performing a genetic screen in mice using Sleeping Beauty (SB) transpos...
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Format: | Thesis |
Language: | English |
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2014
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