Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.

Mice rendered B cell deficient by targeted disruption of the immunoglobulin mu chain gene (IgM-/- mice) were used to analyze the role of antibodies and B cells in viral infections; homozygous IgM-/- mice were bred in a way to avoid transmission of maternal antibodies. After infection with vesicular...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Bründler, M, Aichele, P, Bachmann, M, Kitamura, D, Rajewsky, K, Zinkernagel, R
Formaat: Journal article
Taal:English
Gepubliceerd in: 1996