Genetic loci influencing kidney function and chronic kidney disease.

Genetic loci influencing kidney function and chronic kidney disease.

Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney...

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Bibliografiska uppgifter
Huvudupphovsmän: Chambers, J, Zhang, W, Lord, G, van der Harst, P, Lawlor, D, Sehmi, J, Gale, D, Wass, M, Ahmadi, K, Bakker, S, Beckmann, J, Bilo, H, Bochud, M, Brown, M, Caulfield, M, Connell, J, Cook, H, Cotlarciuc, I, Davey Smith, G, de Silva, R, Deng, G, Devuyst, O, Dikkeschei, L, Dimkovic, N, Dockrell, M
Materialtyp: Journal article
Språk:English
Publicerad: 2010

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