Crystal structure of a human GABAA receptor.

Type-A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABAAR signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional stru...

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Bibliographic Details
Main Authors: Miller, P, Aricescu, A
Format: Journal article
Language:English
Published: 2014