Three's company: component structures bring a closer view of tripartite drug efflux pumps.

Bacterial multidrug resistance is a serious clinical problem and is commonly conferred by tripartite efflux 'pumps' in the prokaryotic cell envelope. Crystal structures of the three components of a drug efflux pump have now been solved: the outer membrane TolC exit duct in the year 2000, t...

Full description

Bibliographic Details
Main Authors: Eswaran, J, Koronakis, E, Higgins, M, Hughes, C, Koronakis, V
Format: Journal article
Language:English
Published: 2004