Analysis of viral diversity for vaccine target discovery

Analysis of viral diversity for vaccine target discovery

BACKGROUND: Viral vaccine target discovery requires understanding the diversity of both the virus and the human immune system. The readily available and rapidly growing pool of viral sequence data in the public domain enable the identification and characterization of immune targets relevant to adapt...

Полное описание

Библиографические подробности
Главные авторы:	Khan, A, Hu, Y, Miotto, O, Thevasagayam, N, Sukumaran, R, Abd Raman, H, Brusic, V, Tan, T, Thomas August, J
Формат:	Journal article
Язык:	English
Опубликовано:	BioMed Central 2017

Схожие документы

Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets.
по: Heiny, A, и др.
Опубликовано: (2007)

A systematic bioinformatics approach for selection of epitope-based vaccine targets.
по: Khan, A, и др.
Опубликовано: (2006)

Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets.
по: A T Heiny, и др.
Опубликовано: (2007-11-01)

Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis
по: Miotto, O, и др.
Опубликовано: (2007)

Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis
по: Miotto, O, и др.
Опубликовано: (2008)

Conservation and variability of dengue virus proteins: implications for vaccine design
по: Khan, A, и др.
Опубликовано: (2008)

Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies
по: Nathaniel L. Miller, и др.
Опубликовано: (2022-06-01)

Extraction by example: Induction of structural rules for the analysis of molecular sequence data from heterogeneous sources
по: Miotto, O, и др.
Опубликовано: (2005)

Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
по: Miotto, O, и др.
Опубликовано: (2008)

Supporting the curation of biological databases with reusable text mining.
по: Miotto, O, и др.
Опубликовано: (2005)

Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
по: Miotto, O, и др.
Опубликовано: (2007)

Complexity of Viral Epitope Surfaces as Evasive Targets for Vaccines and Therapeutic Antibodies
по: Miller, Nathaniel L, и др.
Опубликовано: (2022)

Large-scale analysis of antigenic diversity of T-cell epitopes in dengue virus
по: Srinivasan KN, и др.
Опубликовано: (2006-12-01)

Conservation and variability of West Nile virus proteins.
по: Koo, Q, и др.
Опубликовано: (2009)

FluKB: A Knowledge-Based System for Influenza Vaccine Target Discovery and Analysis of the Immunological Properties of Influenza Viruses
по: Christian Simon, и др.
Опубликовано: (2015-01-01)

Dynamics of Influenza A (H5N1) virus protein sequence diversity
по: Hadia Syahirah Abd Raman, и др.
Опубликовано: (2020-05-01)

Computational discovery of vaccine targets
по: Zhang, Guang Lan
Опубликовано: (2008)

Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.
по: Miotto, O, и др.
Опубликовано: (2010)

Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
по: Tan Tin, и др.
Опубликовано: (2008-02-01)

Conservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.
по: Tan, P, и др.
Опубликовано: (2010)

Coping with viral diversity in HIV vaccine design.
по: David C Nickle, и др.
Опубликовано: (2007-04-01)

Conservation and diversity of influenza A H1N1 HLA-restricted T cell epitope candidates for epitope-based vaccines.
по: Paul Thiamjoo Tan, и др.
Опубликовано: (2010-01-01)

Complete-proteome mapping of human influenza A adaptive mutations: implications for human transmissibility of zoonotic strains.
по: Olivo Miotto, и др.
Опубликовано: (2010-02-01)

Ion Channels as Therapeutic Targets for Viral Infections: Further Discoveries and Future Perspectives
по: Frank W. Charlton, и др.
Опубликовано: (2020-08-01)

ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization.
по: Pappalardo, F, и др.
Опубликовано: (2009)

West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligands.
по: Jung, K, и др.
Опубликовано: (2012)

Optimizing Viral Discovery in Bats.
по: Cristin C W Young, и др.
Опубликовано: (2016-01-01)

Viral vector vaccines
по: McCann, N, и др.
Опубликовано: (2022)

Conservation and variability of West Nile virus proteins.
по: Qi Ying Koo, и др.
Опубликовано: (2009-01-01)

Proteins as Targets in Anti-Schistosomal Drug Discovery and Vaccine Development
по: Ndibonani Kebonang Qokoyi, и др.
Опубликовано: (2021-07-01)

CROSSING: THE DISCOVERY OF YOURSELF
по: Francieli Cristina Miotto
Опубликовано: (2010-08-01)

Development of Universal Influenza Vaccines Targeting Conserved Viral Proteins
по: Seyed Davoud Jazayeri, и др.
Опубликовано: (2019-11-01)

Viral Nucleases from Herpesviruses and Coronavirus in Recombination and Proofreading: Potential Targets for Antiviral Drug Discovery
по: Lee R. Wright, и др.
Опубликовано: (2022-07-01)

Targeted Metagenomics as a Tool to Tap Into Marine Natural Product Diversity for the Discovery and Production of Drug Candidates
по: Marla eTrindade, и др.
Опубликовано: (2015-08-01)

A platform technology for generating subunit vaccines against diverse viral pathogens
по: Andrew Young, и др.
Опубликовано: (2022-08-01)

Dissecting the dynamics of HIV-1 protein sequence diversity.
по: Yongli Hu, и др.
Опубликовано: (2013-01-01)

Massively-multiplexed epitope mapping techniques for viral antigen discovery
по: Diya Hu, и др.
Опубликовано: (2023-09-01)

Recent advances and application of generative adversarial networks in drug discovery, development, and targeting
по: Satvik Tripathi, и др.
Опубликовано: (2022-12-01)

Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription.
по: Ming Li, и др.
Опубликовано: (2021-08-01)

The evolution of viral diversity
по: Wikramaratna, P
Опубликовано: (2012)