Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
With over 450 genes, solute carriers (SLCs) constitute the largest transporter superfamily responsible for the uptake and efflux of nutrients, metabolites, and xenobiotics in human cells. SLCs are associated with a wide variety of human diseases, including cancer, diabetes, and metabolic and neurolo...
मुख्य लेखकों: | Digles, D, Ingles-Prieto, A, Dvorak, V, Mocking, TAM, Goldmann, U, Garofoli, A, Homan, EJ, Di Silvio, A, Azzollini, L, Sassone, F, Fogazza, M, Bärenz, F, Pommereau, A, Zuschlag, Y, Ooms, JF, Tranberg-Jensen, J, Hansen, JS, Stanka, J, Sijben, HJ, Batoulis, H, Bender, E, Martini, R, IJzerman, AP, Sauer, DB, Huber, KVM |
---|---|
स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Frontiers Media
2024
|
समान संसाधन
-
Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily
द्वारा: Daniela Digles, और अन्य
प्रकाशित: (2024-07-01) -
The development of a novel high-throughput membrane potential assay and a solid-supported membrane (SSM)-based electrophysiological assay to study the pharmacological inhibition of GLUT9/SLC2A9 isoforms in a drug discovery program
द्वारा: Antje Pommereau, और अन्य
प्रकाशित: (2024-12-01) -
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters
द्वारा: Vojtech Dvorak, और अन्य
प्रकाशित: (2021-08-01) -
CD4 and the immunoglobulin superfamily.
द्वारा: Barclay, A, और अन्य
प्रकाशित: (1993) -
THE IMMUNOGLOBULIN SUPERFAMILY
द्वारा: Jones, E
प्रकाशित: (1993)