Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels

Random mutagenesis screening indicates the absence of a separate H+-sensor in the pH-sensitive Kir channels

अन्य संस्करण दिखाएं (2)

Several inwardly-rectifying (Kir) potassium channels (Kin l 1, Kir41 and Kir4 2) are characterised by their sensitivity to inhibition by intracellular H+ within the physiological range The mechanism by which these channels are regulated by intracellular pH has been the subject of intense scrutiny fo...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Paynter, J, Shang, L, Bollepalli, M, Baukrowitz, T, Tucker, S
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	LANDES BIOSCIENCE 2010

समान संसाधन

Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels.
द्वारा: Paynter, J, और अन्य
प्रकाशित: (2010)

Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels.
द्वारा: Paynter, J, और अन्य
प्रकाशित: (2010)

Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing.
द्वारा: Rapedius, M, और अन्य
प्रकाशित: (2007)

Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel.
द्वारा: Rapedius, M, और अन्य
प्रकाशित: (2006)

H bonding at the helix-bundle crossing controls gating in Kir potassium channels.
द्वारा: Rapedius, M, और अन्य
प्रकाशित: (2007)

Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1.
द्वारा: Pessia, M, और अन्य
प्रकाशित: (2001)

Insights into the structural nature of the transition state in the Kir channel gating pathway.
द्वारा: Fowler, P, और अन्य
प्रकाशित: (2014)

Differential pH sensitivity of Kir4.1 and Kir4.2 and their modulation by heteropolymerisation with Kir5.1
द्वारा: Pessia, M, और अन्य
प्रकाशित: (2001)

Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels.
द्वारा: Casamassima, M, और अन्य
प्रकाशित: (2003)

Conformational rearrangements during PIP2 gating in Kir channels
द्वारा: Rapedius, M, और अन्य
प्रकाशित: (2007)

A Structural Model of a Kir Channel in the Open State Derived from Mutagenic Scanning of the Pore Gating Energetics
द्वारा: Bollepalli, M, और अन्य
प्रकाशित: (2010)

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.
द्वारा: Tucker, S, और अन्य
प्रकाशित: (1997)

Inward rectification in KATP channels: a pH switch in the pore.
द्वारा: Baukrowitz, T, और अन्य
प्रकाशित: (1999)

Genetic Inactivation of Kcnj16 Identifies Kir5.1 as an Important Determinant of Neuronal PCO2/pH Sensitivity
द्वारा: D'Adamo, M, और अन्य
प्रकाशित: (2011)

pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia.
द्वारा: Tucker, S, और अन्य
प्रकाशित: (2000)

Structural and thermodynamic characterization of the gating pathway in a K+ channel
द्वारा: Bollepalli, M, और अन्य
प्रकाशित: (2014)

Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis.
द्वारा: Shang, L, और अन्य
प्रकाशित: (2009)

Kir4.1 channels contribute to astrocyte CO2/H+-sensitivity and the drive to breathe
द्वारा: Colin M. Cleary, और अन्य
प्रकाशित: (2024-03-01)

Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels.
द्वारा: Shang, L, और अन्य
प्रकाशित: (2008)

State-dependent network connectivity determines gating in a K+ channel.
द्वारा: Bollepalli, M, और अन्य
प्रकाशित: (2014)

Identification of gain of function mutations in KirBac potassium channels by genetic complementation in K+ auxotrophic strains of E-coli and yeast.
द्वारा: Paynter, J, और अन्य
प्रकाशित: (2007)

Intrinsic sensitivity of Kir1.1 (ROMK) to glibenclamide in the absence of SUR2B. Implications for the identity of the renal ATP-regulated secretory K+ channel.
द्वारा: Konstas, A, और अन्य
प्रकाशित: (2002)

Functional complementation and genetic deletion studies of KirBac channels: Activatory mutations highlight gating-sensitive domains
द्वारा: Paynter, J, और अन्य
प्रकाशित: (2010)

Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains.
द्वारा: Paynter, J, और अन्य
प्रकाशित: (2010)

The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP.
द्वारा: Reimann, F, और अन्य
प्रकाशित: (1999)

Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels.
द्वारा: Rapedius, M, और अन्य
प्रकाशित: (2005)

Structural changes in the cytoplasmic pore of the Kir1.1 channel during pH<sub>i</sub>-gating probed by FRET
द्वारा: Shieh Ru-Chi, और अन्य
प्रकाशित: (2009-03-01)

Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels.
द्वारा: Konstas, A, और अन्य
प्रकाशित: (2003)

Evaluation of Root pH Change Through Gel Containing pH-sensitive Indicator Bromocresol Purple
द्वारा: Aparecida Silva, और अन्य
प्रकाशित: (2018-04-01)

Identification of mutations in Kir5.1 which affect time-dependent activation of heteromeric Kir4.1/Kir5.1 potassium channels
द्वारा: Tucker, S, और अन्य
प्रकाशित: (2002)

Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating
द्वारा: Bavro, V, और अन्य
प्रकाशित: (2012)

Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating.
द्वारा: Bavro, V, और अन्य
प्रकाशित: (2012)

Correction Notice: Evaluation of Root pH Change Through Gel Containing pH-sensitive Indicator Bromocresol Purple
द्वारा: Aparecida Silva, और अन्य
प्रकाशित: (2018-04-01)

Sensitivity of the plant vacuolar malate channel to pH, Ca2+ and anion-channel blockers.
द्वारा: Pantoja, O, और अन्य
प्रकाशित: (2002)

K2P and Kir K+ Channels in Physiological Bilayers
द्वारा: Schmidt, MR, और अन्य
प्रकाशित: (2013)

pH sensitive adsorption of polypeptide/sodium dodecyl sulfate mixtures.
द्वारा: Penfold, J, और अन्य
प्रकाशित: (2006)

How highly charged anionic lipids bind and regulate ion channels.
द्वारा: Tucker, S, और अन्य
प्रकाशित: (2008)

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.
द्वारा: Shang, L, और अन्य
प्रकाशित: (2005)

pH-Sensitive Membranes with Smart Cleaning Capability for Efficient Emulsion Separation and Pollutant Removal
द्वारा: Jiaming Zhang, और अन्य
प्रकाशित: (2021-03-01)

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP.
द्वारा: Tanabe, K, और अन्य
प्रकाशित: (1999)