Mendelian randomization with fine‐mapped genetic data: choosing from large numbers of correlated instrumental variables

Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk factor on an outcome. With fine‐mapped genetic data, there may be hundreds of genetic variants in a single gene region any of which could be used to assess this causal relationship. However, using too...

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Bibliographic Details
Main Authors: Burgess, S, Zuber, V, Valdez-Marquez, E, Sun, B, Hopewell, J
Format: Journal article
Published: Wiley 2017