Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.

The human gamma-globin genes form part of a 5-kb tandem duplication within the beta-globin gene cluster on chromosome 11. Despite a high degree of identity between the two genes, we show that while the upstream Ggamma-globin gene terminates transcription efficiently, termination in the Agamma gene i...

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Bibliographic Details
Main Authors: Plant, K, Dye, M, Lafaille, C, Proudfoot, N
Format: Journal article
Language:English
Published: 2005