ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells.
Islet cell autoantigen of 69kDa (ICA69) is a small GTPase-binding protein of unknown function. ICA69 is enriched in the Golgi complex and its N-terminal half contains a BAR domain, a module that can bind/bend membranes and interacts with phospholipids. Here we show that in insulinoma INS-1 cells ICA...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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