ICA69 is a novel Rab2 effector regulating ER-Golgi trafficking in insulinoma cells.

Islet cell autoantigen of 69kDa (ICA69) is a small GTPase-binding protein of unknown function. ICA69 is enriched in the Golgi complex and its N-terminal half contains a BAR domain, a module that can bind/bend membranes and interacts with phospholipids. Here we show that in insulinoma INS-1 cells ICA...

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Bibliographic Details
Main Authors: Buffa, L, Fuchs, E, Pietropaolo, M, Barr, F, Solimena, M
Format: Journal article
Language:English
Published: 2008