The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks prior to monoubiquitination of FANCD2
The Fanconi Anemia (FA) pathway is important for the repair of DNA interstrand crosslinks (ICL). The FANCD2-FANCI complex is central to the pathway, and localizes to ICLs dependent on its monoubiquitination. It has remained elusive whether the complex is recruited before or after the critical mon...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Published: |
Nature Publishing Group
2016
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