Citrullination of autoantigens: upstream of TNFα in the pathogenesis of rheumatoid arthritis.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by synovial inflammation and destruction of joints. Over 20 years ago, tumour necrosis factor alpha (TNFα) was identified as a key player in a cytokine network, whose multifunctional effects could account for both the inflammati...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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