Citrullination of autoantigens: upstream of TNFα in the pathogenesis of rheumatoid arthritis.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterised by synovial inflammation and destruction of joints. Over 20 years ago, tumour necrosis factor alpha (TNFα) was identified as a key player in a cytokine network, whose multifunctional effects could account for both the inflammati...

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Bibliographic Details
Main Authors: Quirke, A, Fisher, B, Kinloch, A, Venables, P
Format: Journal article
Language:English
Published: 2011