Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.

Neisseria meningitidis is a leading cause of sepsis and meningitis. The bacterium recruits factor H (fH), a negative regulator of the complement system, to its surface via fH binding protein (fHbp), providing a mechanism to avoid complement-mediated killing. fHbp is an important antigen that elicits...

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Hlavní autoři: Jongerius, I, Lavender, H, Tan, L, Ruivo, N, Exley, R, Caesar, J, Lea, S, Johnson, S, Tang, C
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2013