Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.
Neisseria meningitidis is a leading cause of sepsis and meningitis. The bacterium recruits factor H (fH), a negative regulator of the complement system, to its surface via fH binding protein (fHbp), providing a mechanism to avoid complement-mediated killing. fHbp is an important antigen that elicits...
Główni autorzy: | , , , , , , , , |
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Format: | Journal article |
Język: | English |
Wydane: |
Public Library of Science
2013
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