A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis.

The phosphoinositide phosphatidylinositol 4, 5-bisphosphate (PtdIns(4,5)P(2)) is essential for many cellular processes and is linked to the etiology of numerous human diseases . PtdIns(4,5)P(2) has been indirectly implicated as a negative regulator of apoptosis ; however, it is unclear if apoptotic...

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Détails bibliographiques
Auteurs principaux: Halstead, JR, van Rheenen, J, Snel, M, Meeuws, S, Mohammed, S, D'Santos, C, Heck, A, Jalink, K, Divecha, N
Format: Journal article
Langue:English
Publié: 2006