Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia.

BACKGROUND: Existing animal models of anemia inadequately reflect the hematocrit usually present in chronic renal failure (CRF) patients and do not permit long-term treatment studies. The transgenic mouse strain 134.3LC (Epo-TAg(H)) displays a severe chronic anemia resembling that observed clinical...

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Bibliographic Details
Main Authors: Rinsch, C, Dupraz, P, Schneider, B, Déglon, N, Maxwell, P, Ratcliffe, P, Aebischer, P
Format: Journal article
Language:English
Published: 2002