Effects of interleukin-6 on the metabolism of connective tissue components in rheumatoid synovial fibroblasts.
OBJECTIVE: High levels of interleukin-6 (IL-6) have been found in the synovial fluid of patients with rheumatoid arthritis (RA). We undertook the present study to investigate the role of IL-6 in this disease. METHODS: We examined the effects of IL-6, in comparison with IL-1, on the biosynthesis of e...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1992
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