Effects of interleukin-6 on the metabolism of connective tissue components in rheumatoid synovial fibroblasts.

OBJECTIVE: High levels of interleukin-6 (IL-6) have been found in the synovial fluid of patients with rheumatoid arthritis (RA). We undertook the present study to investigate the role of IL-6 in this disease. METHODS: We examined the effects of IL-6, in comparison with IL-1, on the biosynthesis of e...

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Bibliographic Details
Main Authors: Ito, A, Itoh, Y, Sasaguri, Y, Morimatsu, M, Mori, Y
Format: Journal article
Language:English
Published: 1992