The role of the lysine demethylases KDM5 and KDM6 in bone malignancies

<p>Methylation of histone lysine residues functions as a dynamic, reversible mechanism for regulating gene expression and aberrations in this process have been linked with the development of cancer. Members of the lysine demethylase (KDM) family remove methyl marks from histones. KDM5B remove...

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Bibliographic Details
Main Author: Hookway, E
Other Authors: Oppermann, U
Format: Thesis
Language:English
Published: 2016
Subjects: