Structure of CrmE, a virus-encoded tumour necrosis factor receptor.
Vaccinia virus (VACV), the smallpox vaccine, encodes many proteins that subvert the host immune response. One of these, cytokine response modifier E (CrmE), is secreted by infected cells and protects these cells from apoptotic challenge by tumour necrosis factor alpha (TNFalpha). We have expressed r...
Main Authors: | , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2007
|