Structure of CrmE, a virus-encoded tumour necrosis factor receptor.
Vaccinia virus (VACV), the smallpox vaccine, encodes many proteins that subvert the host immune response. One of these, cytokine response modifier E (CrmE), is secreted by infected cells and protects these cells from apoptotic challenge by tumour necrosis factor alpha (TNFalpha). We have expressed r...
Main Authors: | Graham, S, Bahar, M, Abrescia, N, Smith, G, Stuart, D, Grimes, J |
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Format: | Journal article |
Language: | English |
Published: |
2007
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