Optimising methods for determining RER status in colorectal cancers.
Approximately 13% of colorectal cancers display microsatellite instability (MSI), a form of replication error repair. Colorectal cancers developing in individuals with constitutional defects in the mismatch repair (MMR) genes hMLH1, hMSH2, hPMS1 and hPMS2 consistently show evidence of this phenomeno...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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